Atopic Dermatitis Clinical Analysis

Children atopic dermatitis clinical analysis

Abstract: Objective: To investigate the clinical treatment of children with atopic dermatitis. Methods: 120 cases of atopic dermatitis in children were randomly divided into the treatment group and the control group, 60 cases in each treatment group received tacrolimus Division jointly loratadine given treatment control group treated with oral loratadine given treatment, compared two groups. Results: The total effective rate was 88.33%, the control group, the total effective rate of 60.0% between the two groups, the difference was statistically significant (P <0.05 recurrence rate of treatment group was 18.33%, compared with 51.67% of the control group, the difference was statistically significant (P <0.05, treatment group, adverse reaction rate was 20.22% and 19.58% in the control group, two groups, the difference was not statistical significance (P> 0.05. Conclusions: tacrolimus Division jointly loratadine, he will be treatment of children with atopic dermatitis efficacy and low incidence of adverse reactions, it is a safe and effective for external use.

Keywords: children, atopic dermatitis, clinical

Atopic dermatitis (Atopicdermatitis, AD, also known as atopic dermatitis, atopic dermatitis, is a chronic, recurrent, allergic skin diseases [1] and more seizures in childhood, how to quickly eliminate clinical skin lesions, improving the quality of life of children and to reduce the repeated distress of AD, dermatologists research, Articles tacrolimus Division jointly loratadine, he will be the treatment of children with atopic dermatitis, and achieve better results, the results The report is as follows.

1 Materials and Methods

1.1 General Information: September 2009 to September 2010, the Court of Dermatology were treated atopic dermatitis in children 120 cases were consistent with the child atopic dermatitis diagnostic criteria, including male 61, female 59 cases, age 2 to 11 years, an average of 6.6 years showed papules, erosions, blood crust, moss, and accompanied by diet appetite when diarrhea and other symptoms, children were excluded from fungal and bacterial infections, no serious Medical disorders, no pair tacrolimus Division and loratadine drug allergy, 2 weeks before treatment the system application corticosteroids and immunosuppressants history. 120 patients were randomly divided into a treatment group and the control group, the treatment group, 31 males and 29 females cases, with an average age of 6.1 years, the control group, 30 males and 30 females, average age of 6.8 years, the comparison of the two groups of children in the age, gender, skin lesions and the severity of the difference was not statistically significant (P> 0.05, with comparable sex.

1.2 Methods: Two groups of children were to disable other allergy medication and topical formulations. Treatment group of 60 patients were treated with tacrolimus Division jointly loratadine given treatment, the the loratadine dose of 5 mg / night oral, he tacrolimus ointment concentration of 0.03%, in the affected area twice daily topical 1, each dose should be spaced about 10 ~ 14 h, the course of a month. control group of 60 patients given oral loratadine.

1.3 The evaluation standard [2]: Points dropped index = total points (before treatment - after treatment, total points / total score before treatment × 100% healed: integral index decreased> 90%, effective in 60% to 89%: efficacy index improved: the efficacy index of 20% to 59%, <20% as invalid to heal + markedly in mind the as valid.

1.4 Statistical Methods: SPSS 13.0 software for data analysis, count data using χ2 test, measurement data using a paired t-test, P <0.05 for the difference was statistically significant.

2 Results

The 2.1 treatment effect comparison: the treatment group, 36 cases were cured, 17 cases, total effective rate was 88.33%, the control group, 17 cases were cured, 19 cases markedly, with a total effective rate of 60.0% between the two groups, the difference was statistically Significance (P <0.05 Table 1.

Table 1 treatment effect [cases (%]

Groups markedly improved the number of patients with healed invalid efficiency (% treatment group,